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The thyroid is an important endocrine organ in the human body, which has the function of synthesizing thyroxine and triiodothyronine. The related diseases caused by abnormal thyroid function are common clinical diseases. Thyroid function examination can provide help for clinical prevention, diagnosis and treatment of organ function damage and substance metabolism disorder caused by abnormal thyroid function.
TSHR is a macromolecular glycoprotein located in the follicular cell membrane of the thyroid gland and belongs to the G protein-coupled receptor superfamily, which is the main antigen of toxic diffuse goiter. It is divided into 3 parts: extracellular, transmembrane and intracellular regions.
| Cat.No. | Product Name | Application-Platform | Product Description |
|---|---|---|---|
| HA134-1H | TSHR Antibody | Detection-CLIA | Humanized Antibody |
| HP134-8 | TSHR Antigen | Capture-CLIA | CHO |
TSH is produced in specific basophilic cells of the anterior pituitary gland, and the release of TSH from the pituitary gland is the central regulatory mechanism by which the body exerts its physiological effects on thyroxine, stimulating the production and secretion of thyroxine; TSH testing is the primary screening test to identify thyroid function, and small changes in free thyroid hormone concentrations can bring about significant adjustments in TSH concentrations in the opposite direction.
| Cat.No. | Product Name | Application-Platform | Product Description |
|---|---|---|---|
| HA147-1M | TSH Antibody | Detection-FIA/CLIA | Mouse Antibody, specific to complete TSH |
| HA147-2M | TSH Antibody | Capture-FIA/CLIA | Mouse Antibody, specific to β-subunit |
| HP147-1 | TSH Antigen | Quality Control-FIA/CLIA | CHO, full-length sequence |
T3, also known as triiodothyronine, is a tyrosine containing iodine, which is synthesized in the thyroid gland cells using iodine and tyrosine as raw materials. When the thyroid gland is subjected to TSH and thyroid hormone is released, the glandular epithelial cells first swallow the thyroglobulin in the follicular cavity into the glandular cells by swallowing, and under the action of lysosomal protein hydrolase, the thyroglobulin is broken down, and the liberated T4 and T3 can enter the blood circulation through the capillaries.
| Cat.No. | Product Name | Application-Platform | Product Description |
|---|---|---|---|
| HA123-7R | T3 Antibody | Detection-FIA | Rabbit Antibody, suitable for tT3 and fT3 |
| HA123-2S | T3 Antibody | Capture-CLIA | Sheep Antibody, suitable for tT3 and fT3 |
| HP123-1 | T3-KLH-BGG | Capture-FIA | T3 Conjugate |
T4 is the most secreted hormone in the thyroid gland, and its metabolic regulation, like that of T3, is controlled by the hypothalamic-anterior pituitary-thyroid axis; the biological activity of T4 is lower than that of T3.
| Cat.No. | Product Name | Application-Platform | Product Description |
|---|---|---|---|
| HA123-5S | T4 Antibody | Capture-CLIA | Sheep Antibody, suitable for tT4 and fT4 |
| HA123-9R | T4 Antibody | Detection-FIA | Rabbit Antibody, suitable for tT4 and fT4 |
| HP123-4 | T4-KLH-BGG | Capture-FIA | T4 Conjugate |
Thyroglobulin (Tg) is a large glycoprotein (MW=660,000) stored in the follicular gel of the thyroid gland. Thyroglobulin is the hormone that synthesizes T4 and T3 within the thyroid gland. Thyroglobulin (Tg) is secreted by thyroid follicular epithelial cells and is the precursor protein for thyroid hormone synthesis and storage. elevated serum Tg levels are associated with three factors: goiter; inflammation and damage to thyroid tissue; and thyroid stimulation by TSH, hCG or TRAb.
| Cat.No. | Product Name | Application-Platform | Product Description |
|---|---|---|---|
| HA144-10M | Tg Antibody | Detection-CLIA | Mouse Antibody |
| HA144-12M | Tg Antibody | Capture-CLIA | Mouse Antibody |
