Clinical Significance

Glycated hemoglobin (HbA1c) is the product of the combination of hemoglobin in red blood cells with sugars in serum. It is formed by a slow, continuous and irreversible glycation reaction, and its amount depends on the blood glucose concentration and the contact time between blood glucose and hemoglobin, independent of the time of blood draw, whether the patient is fasting or not, and whether he is using insulin or not.

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