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Protein Induced by Vitamin K Absence or Antagonist-II(PIVKA-II)

Clinical Significance

Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II) is a protein that is induced by vitamin K deficiency or antagonist-II in the human body (PIVKA-II), also known as de-γ-carboxyprothrombin (DCP). Normal prothrombin is synthesized by hepatocytes. The only difference between abnormal and normal is that the glutamic acid residue at the specific position of its amino terminus is not carboxylated and is decarboxylated prothrombin.
    Chinese and foreign clinical prevention and treatment guidelines have regarded DCP as a very important indicator for liver cancer detection. It is recommended for screening of high-risk groups, auxiliary diagnosis of liver cancer, monitoring of treatment effects, and as a prediction tool for prognosis and recurrence.

Product Information

Cat.No. Product Name Application-Platform Product Description
HA133-1M PIVKA-II Antibody Detection-CLIA Mouse Antibody, specific to prothrombin
HA133-2H PIVKA-II Antibody Capture-CLIA Humanized Antibody, specific to Gla Domain
HP133-1 PIVKA-II Antigen Quality Control-CLIA E.coli, N-terminal fragment
HP133-2 PIVKA-II Antigen Quality Control-CLIA E.coli, N-terminal fragment