Provide you with the best solution for the use of raw materials
Cardiac troponin is composed of subunits of three distinct genes: cardiac troponin T (cTnT), cardiac troponin I (cTnI), and troponin C (TnC). Cardiac troponin exists in cardiomyocytes in the form of cTnI-CT complex and free cTnI. After myocardial injury is released into the blood circulation, cTnI-CT can be further decomposed into cTnI-C complex and free cTnI, which metabolize The product is excreted by the kidneys. Three isoforms of TnI (troponin I) exist: two skeletal muscle troponin I (sTnI) and cardiac troponin I (cTnI). There is also a 40% difference with the amino acid sequence of the skeletal muscle type.
Due to the small molecular weight of cTnI, free cTn is rapidly released from the cardiomyocytes to the circulatory system after the onset of the disease, and the concentration in the blood increases rapidly. At the same time, due to the sequence difference between cTnI and sTnI, CK and CK-MB may increase when muscle tissue other than myocardium is injured or diseased, while cTnI will not exceed its critical value. Moreover, the content of cTnI in normal serum is very small, and it is significantly increased in AMI, and the increase rate generally exceeds the changes of total CK and CK-MB. Currently, cTnI is mainly used for laboratory AMI diagnosis.
cTnI protein is a polypeptide chain of 210 amino acids. At present, the main monoclonal monoclonal antibody epitopes used in mainstream kits are concentrated in 24-40, 31-49, 86-90, etc. The pairing methods include 1+1, 1+2 and 2+2.
Cat. No. | Product name | Application-Platform | Product Description |
---|---|---|---|
HA101-20M | cTnI Antibody | Detection-Rapid test/FIA | Mouse Antibody, a.a.r. 24-40 |
HA101-13MB | cTnI Antibody | Detection-Rapid test/FIA | Mouse Antibody, a.a.r. 41-49 |
HA101-10M | cTnI Antibody | Capture-Rapid test/FIA | Mouse Antibody, TroponinC |
HA101-11M | cTnI Antibody | Capture-Rapid test/FIA | Mouse Antibody, a.a.r. 83-93 |
HA101-14M | cTnI Antibody | Capture-Rapid test/FIA/CLIA | Mouse Antibody, specific to troponin Complex |
HA101-13H | cTnI Antibody | Detection-CLIA | Humanized Antibody, a.a.r. 41-49 |
HA101-2M | cTnI Antibody | Capture-CLIA | Mouse Antibody, a.a.r. 24-40 |
HA101-7M | cTnI Antibody | Detection-Rapid test/FIA | Mouse Antibody, a.a.r. 86-90 |
HA101-8M | cTnI Antibody | Detection-Rapid test/FIA | Mouse Antibody, a.a.r. 169-178 |
HP101-1 | cTnI Antigen | /-Control | E.coli, (cTnI-C-I) |
HP101-2 | cTnI Antigen | /-Control | E.coli, (cTnI-C-II) |