Clinical Significance

Typhoid fever is a serious infectious disease caused by the bacterium Salmonella enterica serotype Typhi.    It is prevalent in regions with poor sanitation and is transmitted through contaminated food and water.

Diagnosing typhoid fever involves laboratory tests such as blood cultures, stool cultures, and bone marrow cultures to detect the presence of Salmonella Typhi. Serological tests like the Widal test can also be used, although they are less specific.