Product Recommendation I D-Dimer

The fibrinolytic system in the body plays an important role in maintaining the normal permeability of the blood vessel walls, maintaining the flow state of blood and tissue repair. To maintain the normal physiological state, in case of trauma or vascular damage, thrombus is formed in the blood vessels to prevent blood loss from the damaged vessels. When coagulation occurs, thrombin can act on fibrin to convert it into cross-linked fibrin, while the fibrinolytic system is activated to degrade cross-linked fibrin to form various fibrin degradation product (FDP) fragments. In the presence of γ-chain, two D-fragment-containing fibrin fragments can be joined to form D-dimers. Elevated levels of D-dimers in humans predict the presence of secondary hyperfibrinolysis in their bodies.

D-dimer is a characteristic product of cross-linked fibrin degradation that reflects hypercoagulability and hyperfibrinolysis in vivo. Increased or positive levels are seen in secondary hyperfibrinolytic function. Clinically, D-dimer can be elevated in disseminated intravascular coagulation (DIC), deep vein thrombosis (DVT), pulmonary embolism (PE), acute myocardial infarction, cerebral infarction, malignancy, ovarian cancer, lung cancer, sepsis, liver disease, pregnant women with hyperemesis, pre-eclampsia, burns, surgery, trauma, and sepsis, but an elevated D-dimer test does not indicate the cause and location of thrombosis. However, an elevated D-dimer test does not indicate the cause and location of thrombosis and must be analyzed in conjunction with clinical and other tests.    

The reagents are highly sensitive, anti-interference, stable, and compatible with almost all types of hemagglutination and biochemistry instruments at home and abroad, and can be customized according to customers' requirements.